Brain tumors begin when abnormal cells in the brain grow and divide in an uncontrolled way. Because every patient’s situation is unique, our team at Illinois CancerCare focuses on early detection, accurate diagnosis, and personalized treatment plans designed to give you the best possible outcome. Primary brain tumors start in the brain or spinal cord, while secondary (metastatic) brain tumors begin in another part of the body and spread to the brain. This page focuses on primary brain and central nervous system (CNS) tumors.  

Understanding the Brain & CNS

The brain and spinal cord make up the central nervous system, which controls how we think, feel, move, and process information. Brain tumors can be benign (noncancerous) or malignant (cancerous); both can cause symptoms by pressing on or invading nearby brain tissue. Unlike many other cancers, brain tumors don’t use a standard “TNM” staging system—doctors focus on tumor type, grade, location, and molecular features to guide treatment.  

Types of Brain Tumors

There are many kinds of primary brain tumors. In adults, common types include: 

Gliomas

(e.g., astrocytoma, oligodendroglioma, glioblastoma)

Meningioma

(arises from the brain’s protective membranes; often benign)

Schwannoma

(nerve sheath tumor; often benign)

Pituitary tumors 

Primary CNS lymphoma 

Medulloblastoma and other rare tumors

(more common in children, but can occur in adults) 

Your care team will explain which type you have and what it means for treatment and recovery.  

Signs & Symptoms

Symptoms depend on tumor type and location and may include: 

  • Headaches (often worse in the morning or with activity) 
  • Nausea or vomiting 
  • Seizures 
  • Vision, speech, or hearing changes 
  • Weakness, numbness, or problems with balance 
  • Memory, personality, or cognitive changes

If you notice persistent or worsening symptoms, talk with your doctor. 

Risk Factors

Most brain tumors have no clearly known cause, but factors linked with higher risk include: 

  • Previous radiation exposure to the head 
  • Certain inherited conditions (e.g., LiFraumeni syndrome, neurofibromatosis) 
  • Family history of specific tumor types 

Having a risk factor doesn’t mean you will develop a brain tumor, and many people diagnosed have no identifiable risks.  

Screening

There is no standard screening test for people at average risk of primary brain tumors. Evaluation usually begins when symptoms appear or when a brain abnormality is found on imaging done for another reason.  

Diagnosis

Your diagnosis and treatment plan are informed by several steps: 

to check strength, reflexes, vision, balance, and cognition

  • MRI with contrast (primary test) to define tumor location and extent 
  • CT scan when MRI isn’t possible or to assess bone or acute changes 
  • Advanced imaging (e.g., functional MRI) when planning surgery near critical brain areas 

to confirm diagnosis and determine tumor grade

(for certain tumors) To identify features that can guide therapy

Your team will tailor testing to your situation and explain what each result means.  

Grading

Instead of TNM staging, brain tumors are classified by grade (how abnormal the cells appear and how quickly they tend to grow) and by molecular markers that can inform prognosis and treatment choices. Your care team will review the grade and key markers relevant to your tumor type.  

Treatment Options

Treatment is individualized based on tumor type, grade, location, molecular features, overall health, and your goals. Care is coordinated by a multidisciplinary team experienced in neurooncology. 

Watchful waiting (active surveillance)

for some slow-growing, asymptomatic tumors

Surgery

to remove as much tumor as safely possible; advanced techniques and mapping may help preserve function

Radiation Therapy  

  • Externalbeam radiation (including IMRT) 
  • Stereotactic radiosurgery (focused, highdose radiation for select tumors) 
  • Proton therapy at specialized centers, when appropriate 

Chemotherapy

(e.g., temozolomide for certain gliomas)

Targeted therapy & immunotherapy

for select tumor types/biomarkers

Tumor Treating Fields (TTF)

for eligible patients with specific gliomas

Rehabilitation & supportive care

(physical/occupational/speech therapy, seizure management, symptom control)

Your Illinois CancerCare team will discuss benefits and potential side effects and whether a clinical trial may be right for you.  

Prognosis

Many brain tumors are treatable, especially when found early and when surgery can safely remove most or all of the tumor. Prognosis depends on tumor type, grade, molecular features, location, extent of resection, and response to therapy. Your doctor will explain what these factors mean in your case.  

Follow Up Care

Followup typically includes regular MRI scans, physical and neurologic exams, and monitoring for treatment effects or recurrence. Your plan may also include rehabilitation services and support for cognitive or emotional changes that can occur after treatment.  

Living With a Brain Tumor

Illinois CancerCare offers comprehensive support, including counseling, nutrition guidance, rehabilitation, survivorship programs, caregiver resources, and access to clinical trials—all designed to help you and your loved ones navigate treatment and recovery. National organizations such as the American Brain Tumor Association also offer education, peer support, and financial resources.  

Why Choose Illinois CancerCare

  • Experienced neurooncology care close to home 
  • Advanced diagnostics and coordinated care with neurosurgery and radiation oncology partners 
  • Access to innovative treatments and clinical trials through our active research program 
  • Compassionate, patient-centered care focused on preserving function and quality of life 

See our Current Clinical Trials page for studies that may be available to you.

Sources & Patient Friendly References

All information was taken from the NCI (National Cancer Institute) and ACS (American Cancer Society).